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Offsetting Hippocampal Degeneration in m-sTBI

Traumatic Brain Injury | Degeneration | Memory; Loss, Mild, Following Organic Brain Damage

The goal of this study is to establish the feasibility of an intervention designed to improve memory in patients who have experienced a moderate or severe traumatic brain injury (m-sTBI) and to examine its effect on brain structures.

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Conditions de participation

  • Sexe:

    ALL

  • Âges admissibles:

    18 to 65

Critères de participation

Inclusion Criteria:

* An acute care diagnosis of TBI as determined by a medical professional, indicated by:

* Post-traumatic amnesia duration of 24 hours or more, and/or lowest Glasgow Coma Scale score of \< 13
* Positive clinical CT or MRI scan
* Aged 18 to 65
* Fluent in English
* Have the competency for fully informed consent by 6 months post-injury
* Have basic computer skills
* Have functional use of one upper extremity
* Have access to the internet

Exclusion Criteria:

* A neurological disorder other than TBI (e.g., stroke, dementia, tumor, neurodevelopmental disorder) impairing baseline awareness, cognition, or validity of follow-up and outcome assessment.
* A systemic condition (e.g., lupus, diabetes, rheumatoid arthritis).
* Any contraindications to magnetic resonance imaging (MRI)
* You are experiencing language impairments (i.e., aphasia) from your injury

Lieu de l'étude

GF Strong Rehabilitation Centre
GF Strong Rehabilitation Centre
Vancouver, British Columbia
Canada

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Vancouver General Hopsital
Vancouver General Hopsital
Vancouver, British Columbia
Canada

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Étude parrainée par
University of British Columbia
Participants recherchés
Plus d'informations
ID de l'étude: NCT03727334