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Offsetting Hippocampal Degeneration in m-sTBI

Traumatic Brain Injury | Degeneration | Memory; Loss, Mild, Following Organic Brain Damage

The goal of this study is to establish the feasibility of an intervention designed to improve memory in patients who have experienced a moderate or severe traumatic brain injury (m-sTBI) and to examine its effect on brain structures.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 to 65

Participation Criteria

Inclusion Criteria:

* An acute care diagnosis of TBI as determined by a medical professional, indicated by:

* Post-traumatic amnesia duration of 24 hours or more, and/or lowest Glasgow Coma Scale score of \< 13
* Positive clinical CT or MRI scan
* Aged 18 to 65
* Fluent in English
* Have the competency for fully informed consent by 6 months post-injury
* Have basic computer skills
* Have functional use of one upper extremity
* Have access to the internet

Exclusion Criteria:

* A neurological disorder other than TBI (e.g., stroke, dementia, tumor, neurodevelopmental disorder) impairing baseline awareness, cognition, or validity of follow-up and outcome assessment.
* A systemic condition (e.g., lupus, diabetes, rheumatoid arthritis).
* Any contraindications to magnetic resonance imaging (MRI)
* You are experiencing language impairments (i.e., aphasia) from your injury

Study Location

GF Strong Rehabilitation Centre
GF Strong Rehabilitation Centre
Vancouver, British Columbia
Canada

Contact Study Team

Vancouver General Hopsital
Vancouver General Hopsital
Vancouver, British Columbia
Canada

Contact Study Team

Study Sponsored By
University of British Columbia
Participants Required
More Information
Study ID: NCT03727334