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Impact of PEG Bowel Preparation on Gut Microbiome Composition Recovery

Cancer | Healthy Participants

The main objective is to evaluate the impact of intestinal preparation on the composition, diversity and metabolome of the intestinal microbiota.

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Conditions de participation

  • Sexe:

    ALL
  • Âges admissibles:

    18 to 70

Critères de participation

Inclusion Criteria:

* Healthy volunteer participant cohort:

1. \> 18 years of age
2. The participant has provided documented informed consent for the participation and to complete PEG bowel preparation and return collected stool samples.

Exclusion Criteria:

* An ileus
* Significant gastric retention
* Suspected or established mechanical bowel obstruction
* Inflammatory or infectious gastrointestinal condition
* Neurologic or cognitive impairment that prevents safe swallowing
* Recent history (\<1 year) of cancer that still requires ongoing treatment
* Recent use of antibiotics 1 month prior to participation in the trial
* History of cardiac disease
* History of active renal dysfunction
* Presence of any absolute contraindication to PEG bowel preparation according to manufacturer labeling

Lieu de l'étude

Centre hospitalier de l'Université de Montréal (CHUM)
Centre hospitalier de l'Université de Montréal (CHUM)
Montreal, Quebec
Canada

Contactez l'équipe d'étude

Primary Contact

Wiam Belkaid, PhD

[email protected]
514-890-8000
Backup Contact

Alysé Filin, MSc

[email protected]
5148908000
Étude parrainée par
Centre hospitalier de l'Université de Montréal (CHUM)
Participants recherchés
Plus d'informations
ID de l'étude: NCT06831539