Impact of PEG Bowel Preparation on Gut Microbiome Composition Recovery

Participation Requirements

• Sex:

  ALL

• Eligible Ages:

  18 to 70

Participation Criteria

Inclusion Criteria:

* Healthy volunteer participant cohort:

1. \> 18 years of age
2. The participant has provided documented informed consent for the participation and to complete PEG bowel preparation and return collected stool samples.

Exclusion Criteria:

* An ileus
* Significant gastric retention
* Suspected or established mechanical bowel obstruction
* Inflammatory or infectious gastrointestinal condition
* Neurologic or cognitive impairment that prevents safe swallowing
* Recent history (\<1 year) of cancer that still requires ongoing treatment
* Recent use of antibiotics 1 month prior to participation in the trial
* History of cardiac disease
* History of active renal dysfunction
* Presence of any absolute contraindication to PEG bowel preparation according to manufacturer labeling