Skip to content

Treating Postictal Symptoms Using Ibuprofen and Nifedipine

Epilepsy | Epilepsies, Partial

This study will evaluate the effect of ibuprofen or nifedipine on post-seizure hypoperfusion and neurological deficits in patients with epilepsy. One group will receive ibuprofen, another will receive nifedipine, and anther placebo.

null

Conditions de participation

  • Sexe:

    ALL

  • Âges admissibles:

    16 and up

Critères de participation

Inclusion Criteria:

* age \> 16 yrs, frequent seizures (\>1 per week) and cognitive ability sufficient to complete neuropsychological testing.

Exclusion Criteria:

* multiple seizure onset zones, contraindications to CT or MR imaging, any contraindication to ibuprofen or nifedipine, as well as current or recent (\< 2 months) exposure COX-2 inhibitor or calcium channel blocker.

Lieu de l'étude

Foothills Medical Centre
Foothills Medical Centre
Calgary, Alberta
Canada

Contactez l'équipe d'étude

Primary Contact

Paolo Federico, MD, PhD

[email protected]
(403) 944-4091
South Health Campus
South Health Campus
Calgary, Alberta
Canada

Contactez l'équipe d'étude

Primary Contact

Paolo Federico, MD, PhD

[email protected]
403.944.4091
Étude parrainée par
University of Calgary
Participants recherchés
Plus d'informations
ID de l'étude: NCT03949478