The purpose of this research study is to determine if some people diagnosed with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) may have another genetic disease that can cause nerve damage, called hereditary TTR amyloidosis (hATTR). hATTR is treated very differently than CIDP, so understanding if hATTR is sometimes incorrectly diagnosed as CIDP is important.

This study seeks to understand the relationship between brain blood flow and the memory symptoms seen in normal aging, mild cognitive impairment, Alzheimer's disease, and a blood vessel condition called cerebral amyloid angiopathy.

Tremor disorders are often misdiagnosed because they can seem similar during check-ups. This can lead to getting the wrong treatment and prognosis. Sometimes, experts can't tell if someone has Parkinson’s disease for sure. This can lead to many wrong guesses. Essential tremor is misdiagnosed 37% of the time, often as Parkinson’s disease. Because there aren't good tools to diagnose, it's even harder to figure out the problem. Regular imaging tests don't help much either.

To evaluate patient-reported improvement with atogepant for the prevention of migraine in the real-world setting.

We aim to improve the lives of children with significant disabilities by making robotic walking available to a group of children who cannot walk on their own. Robotic gait trainers can be an assistive device to increase physical activity levels for these children, which may reduce consequences of inactivity. We will be providing participants with a Trexo robotic gait trainer for 3 months, and will complete assessments before, during, and after the training period, as well as for a time once the training is complete.

This study aims to explore how memory works in people with temporal lobe epilepsy, a condition that causes seizures and is frequently accompanied by memory problems. For some, surgery to remove the part of the brain causing seizures may help, but it does not always work, and memory can get worse afterward. We aim to use magnetic resonance imaging to image the brain participants are completing memory tasks, which will reveal the areas of the brain responsible for memory. This knowledge could help doctors decide which epilepsy patient might benefit from surgery, how to plan surgery to minimize memory loss, and set realistic expectations for patients about their memory after the procedure. As part of the study, patient participants and healthy controls will look at images of faces and scenes as well as words inside a magnetic resonance scanner. Still inside the scanner, participants will have to attempt to remember the images and words you saw after 20 minutes. This way, we will be able to see the areas in the brain responsible for memorizing as well as remembering. We will also ask participants to complete 1 hour of memory tests outside of the scanner.

This is a long-term study to determine factors associated with outcomes in MS. The purpose of this study is to improve MS care, treatment, and health outcomes. The study uses information from participants' medical records. Additionally, participants can choose to fill out questionnaires or provide a blood sample. These parts are optional. There are no study visits.

The purpose of the Calgary Stroke Program Clinic Register is to determine the risk factors responsible for recurrent stroke and your health utilization over the next 10 years. We will obtain information about recurrent events by tracking the use of health care services (including hospitalizations, emergency room visits, home care service use and admission to care facilities). Patient chart will be reviewed for risk factors and test results. This information will help us determine which vascular risk factors are most responsible for recurrent stroke events. To obtain this information, we will use your personal health care number (PHN). Your clinical data will kept securely for approximately 10 years.

Cervical dystonia and levodopa-induced dyskinesia (or LID) in Parkinson’s disease are two common movement. Our understanding of these conditions is still limited which led to very few treatment options for its motor symptoms. However, the non-motor symptoms are also common in dystonia and LID. One of these non-motor symptoms is the poor sleep quality. Dr. Davide Martino at the University of Calgary is leading a research study to gain a better understanding of the brain activity during the sleep (better known as the sleep architecture) and the quality of sleep in the people diagnosed with dystonia and LID. This study aims to gain a better understanding of this non-motor aspect of dystonia and LID. This is an observational study. Complete participation in the study comprises a single visit followed by 7 nights of recording of your sleep at your home. The study duration depends on your schedule and availability. As part of this study, we will ask you to undergo one clinical assessment involving physical examination and questionnaires about your mood, anxiety, and sleep quality.

We are looking for front line care providers (nurses, midwives, physicians) to speak with us in a short (~30 minute) interview. If you are someone who provides care during pregnancy orthe postpartum in the Cayman Islands, we need your input! Researchers from the University College of the Cayman Islands and the University of Calgary (Canada) have teamed up to try and understand the experiences of parents and caregivers in the Cayman Islands with the types of support available in pregnancy and after having a new baby. Our study aims to improve the support and health service experiences of parents in the Cayman Islands in the first few months after birth. Parenting a new infant is often an extremely busy time that involves changes in sleep, family interactions, daily activities, social life etc. Some parents find it stressful, and can experience challenges with caring for their infants. Some examples of common challenges include feeding difficulties, lack of sleep, isolation, and stress. Our team is partnering with the University College of the Cayman Islands and the Cayman Islands Ministry of Health and Wellness to try and understand the experiences of new parents in order to improve and/or create new services and supports in the Cayman community, to help families through the transitions involved with parenting a new baby.