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This study will compare the cosmetic scar result from the use of scalpel, electrocautery, and pulsed electron avalanche knife (PEAK) PlasmaBlade (PPB) for the initial skin incision for total mastectomy procedures without immediate breast reconstruction. It is hypothesized that there will be no significant difference in mastectomy scar cosmesis. The purpose and objectives of this study are: 1. To evaluate and compare the cosmetic scar result from the use of scalpel, standard electrocautery, or PEAK PlasmaBlade for initial incision for total mastectomy procedures without immediate breast reconstruction. 2. To inform future equipment choices for breast surgery including potential elimination of scalpels and their attendant risks.

Conditions:
Surgical Wound Infection | Post-operative Pain | Postoperative Complications | Wound Complication | Scar
Location:
  • Mount Saint Joseph Hospital, Vancouver, British Columbia, Canada
Sex:
ALL
Ages:
Any

Early childhood is an important period where the family can support the development and maintenance of healthy eating and active behaviors to prevent or reduce childhood obesity. With this ultimate goal, we designed the Good Start Matters - Parenting program, which aims to engage families in positive parenting practices that support healthy child behaviors, and aim to evaluate the efficacy of this intervention with a Randomized Controlled Trial (RCT). The Good Start Matters - Parenting program is a 2-month mobile-Health (mHealth) parenting intervention which promote positive parenting (primary outcome) and support children's healthy nutrition, physical activity, and decrease screen-time (secondary outcomes).

Conditions:
Parenting Practices | Co-parenting Practices | Child Eating and Dietary...
Location:
  • University of British Columbia / BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada
Sex:
ALL
Ages:
3 - 6

The goal of this intervention study is to test the effects of a nurse-led mobility intervention (known as the OASIS Walking Intervention (Older Adults performing Sit to Stands and Walking Intervention)) in older adults with cognitive impairment, such as dementia, in transitional care programs. The main questions this study aims to answer are: * Is the study doable and are older adults satisfied with the intervention? * Does the intervention improve older adults' muscle strength, mobility, functional status and quality of life? Participants will be asked to do the following: 1. Be interviewed once so that a patient-centred communication care plan can be made 2. Do sit to stand activity 3. Walk as part of a walking program.

Conditions:
Cognitive Impairment | Dementia | Delirium | Functional Decline
Location:
  • Cedarbrook Lodge Retirement Home Transitional Care Unit (Operated by Bayshore Health Care), Scarborough, Ontario, Canada
  • Abbeylawn Retirement Home Transitional Care Unit (Operated by Bayshore Health Care), Pickering, Ontario, Canada
  • Cedarbrook Lodge Retirement Home Transitional Care Unit (Operated by Bayshore Health Care), Scarborough Village, Ontario, Canada
Sex:
ALL
Ages:
Over 65

This study aims to explore the patients' and providers' perspectives and inform future anesthetic practice for patients undergoing unexpected cesarean delivery (CD) under neuraxial anesthesia (NA). The consideration of patients' concerns, preferences, expectations, and suggestions may lead to enhanced patient satisfaction, compliance, and quality of care that future patients receive during unexpected CD under NA. The investigators will possibly be able to identify gaps in procedural performance that warrant further investigation during the second phase of this study which will contribute to improvement of overall patient care. During the third phase, educational material will be generated from patient insights and will be distributed to the Department of Anesthesia, Department of Obstetrics and Gynaecology, Labour and Delivery Nurses and team of Anesthesia Assistants and Respiratory Therapists.

Conditions:
Psychological Well Being
Location:
  • Mount Sinai Hospital, Toronto, Ontario, Canada
Sex:
FEMALE
Ages:
18 - 50

The study aims at examining the impact of an immersive and interactive digital application (App) that uses impressionist artworks to promote the mental well-being of both young and older adults. The goal is to study the usability and accessibility of this App, particularly for older adults, who may have sensory impairments and lower digital literacy compared to younger adults. The study is based on the hypothesis that the App, which allows interaction with paintings by Claude Monet and Helen McNicoll, can trigger positive emotions, thereby improving users' well-being. The App uses artificial intelligence to create extensions of the paintings and music based on the sonification of electrophysiological signals captured from plants. The study seeks to answer four research questions: 1. The usage behaviors of young and older adults with the App. 2. The impressions and feedback from users after testing the App. 3. The obstacles and enablers to the App's use. 4. The expectations and needs of users for better use of the App. The study's objectives include analyzing the usage behaviors, impressions, barriers, and needs of both young and older adults. It is a qualitative study based on non-participatory observations and semi-structured interviews with young and older participants who have used the App. The App is based on impressionist artworks, a style known for evoking positive emotions, and aims to promote mental health by harnessing the emotional power of digital art and artificial intelligence.

Conditions:
Adults
Location:
  • CRIUGM, Montreal, Quebec, Canada
Sex:
ALL
Ages:
Over 18

The purpose of this study is to compare how effective and how tolerable two different bowel preparation laxatives are for colonoscopy. The aim is to compare oral sulfate solution (OSS) to another laxative called 2L polyethylene glycol (PEG) solution to see which is more effective and more tolerable by individuals with IBD (Crohn's disease or Ulcerative colitis).

Conditions:
Crohn Disease | Ulcerative Colitis
Location:
  • University of Manitoba, Winnipeg, Manitoba, Canada
Sex:
ALL
Ages:
Over 18

Caudal analgesia is an effective intervention for lumbosacral pain. Some chronic pain patients take anticoagulants for vasculopathy treatment. Anticoagulation limits the use of caudal analgesia because of the risk of epidural bleeding. Caudal analgesia may be safe and effective in anticoagulated chronic pain patients. Quantitative analysis of prospective clinical data. Evaluation of caudal analgesia efficacy and safety in anticoagulated chronic pain patients. Analysis of outcome, and complications.

Conditions:
Anticoagulants and Bleeding Disorders | Lumbar Pain Syndrome
Location:
  • Salem Anaesthesia Pain Clinic, Surrey, British Columbia, Canada
Sex:
ALL
Ages:
20 - 99

This is a pilot research study to test the protocols needed for transcutaneous spinal electrical stimulation in persons living with spinal cord injury (SCI). Up to 24 participants will be enrolled. A variety of stimulation parameters and outcome measures will be assessed.

Conditions:
Spinal Cord Injuries | Paraplegia, Spinal | Spinal Cord Injury at C5-C7 Level | Paraplegia, Incomplete
Location:
  • University of Manitoba, Winnipeg, Manitoba, Canada
Sex:
ALL
Ages:
18 - 65

The purpose of this research is to determine whether extra betaine and choline influence metabolic health in adults with overweight and obesity.

Conditions:
Obesity and Obesity-related Medical Conditions
Location:
  • Human Nutraceutical Research Unit, Guelph, Ontario, Canada
Sex:
ALL
Ages:
18 - 70

Atrial fibrillation is an abnormal heart rhythm in which can increase the risk of developing clots in the heart which can then break off and travel to the brain and cause a stroke. Catheter ablation is a procedure which is used to restore the regular rhythm of the heart; however even when this treatment is successful, patients still may have an increased risk of having a stroke compared to people who have never had atrial fibrillation. Two types of medication are presently prescribed to patients following their catheter ablation (even if it appears to have been successful in eliminating atrial fibrillation): an antiplatelet (such as aspirin), or an anticoagulant (also known as a blood thinner). This study is being done in order to find out which type of medication works best for preventing strokes in people who have had a successful catheter ablation.

Conditions:
Atrial Fibrillation
Location:
  • Victoria Cardiac Arrhythmia Trials Inc., Victoria, British Columbia, Canada
  • St. Mary's General Hospital, Kitchener, Ontario, Canada
  • Scarborough Health Network- Rougevalley, Toronto, Ontario, Canada
  • Centre Hospitalier de L'Universite de Montreal (CHUM), Montreal, Quebec, Canada
  • Institut Universitarie de Cardiologie et de Pneumologie de Quebec, Québec, Quebec, Canada
  • Royal Columbian/Fraser Clinical Trials, New Westminster, British Columbia, Canada
  • Hamilton Health Sciences Centre, Hamilton, Ontario, Canada
  • Southlake Regional Health Centre, Newmarket, Ontario, Canada
  • Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
  • McGill University Health Centre, Montreal, Quebec, Canada
  • St. Paul's Hospital, Vancouver, British Columbia, Canada
  • Kingston General Hospital, Kingston, Ontario, Canada
  • University of Ottawa Heart Institute, Ottawa, Ontario, Canada
  • Sherbrooke- Grandby site, Granby, Quebec, Canada
  • Montreal Health Institute, Montreal, Quebec, Canada
  • Foothills Medical Centre, Calgary, Alberta, Canada
  • Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
  • London Health Sciences Centre, London, Ontario, Canada
  • St. Michael's Hospital, Toronto, Ontario, Canada
  • Hôpital du Sacré-Coeur de Montreal, Montreal, Quebec, Canada
  • Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada
  • University of Calgary, Calgary, Alberta, Canada
Sex:
Male, Female, Intersex
Ages:
18 - 85