We are aiming to show that running an air purifier in the bedroom of a child with uncontrolled asthma will help them improve asthma control. To prove that the air purifier is working, we will keep track of air quality in the bedroom and the home. We will measure asthma and sleep quality with monthly questions and breathing tests. We will also check urine for chemicals from the air. By checking chemicals in the air, how the body takes them in and asthma at the same time we can show whether the air purifier truly helps.

To see if ADDING a new biologic (ianalumab) improves lupus of patients with active lupus despite the medications they are taking. Participants will be randomly assigned, like flipping a coin, to one of three groups and will have a: 3 in 7 chance of receiving ianalumab every 4 weeks 3 in 7 chance of receiving ianalumab every 12 weeks. 2 in 7 chance of receiving placebo (fake study drug). It is given by injection (two at each visit) into the fatty layer of the arms, abdomen or thighs. There may be up to 27 visits over a maximum of 2 years.

Patients with COVID-19 may experience prolonged physical and psychological symptoms after weeks or months of the infection. This may be caused by a combination of factors including poor nutrition, low physical activity, and lack of emotional support. Leading to poor overall health and low quality of life. This evidence indicated that people with long COVID-19 need a personalized intervention. Our objective is to determine if the use of an online application that is based on preventive self-care and that includes nutrition and mindfulness will be feasible to use for patients with long COVID.

The purpose of this study is to explore how Spiritual Health Practitioners (SHP) currently experience your own competent spiritual care practice in healthcare settings in Alberta. This information will help SHP’s, students and other important stakeholders better understand what competent spiritual care practice looks like from the perspective of someone who is presently engaged in the work.

Achondroplasia (ACH) is the most common form of skeletal abnormality. Currently, there is no agreement about the best way to treat ACH. Current treatment options, aimed at preventing or treating complications of ACH, may be painful and are not guaranteed to be effective. The purpose of this study is to collect data on the growth pattern of children with ACH.

The purpose of this study is to develop a group exercise program to support pelvic floor care for women living in rural remote areas of Alberta, who are experiencing urinary incontinence. Amendment: 2024-03-07 In addition to the exercise protocol, we aim to understand the demands for pelvic floor care in rural Alberta by conducting a needs assessment survey across all genders. Amendment: 2024-09-23 The purpose of this study is to assess the benefits of the exercise program developed in the pilot project between same and different age brackets.

The purpose of this study is to develop parental educational tools (that use art and digital platforms) for emergency room settings. The condition that will be reviewed in this study is COVID-19. Using this approach to deliver information to parents and caregivers, we hope to reduce uncertainty and improve knowledge around the illness itself and what families and children can expect. We are looking to interview (1) parents of children who have been diagnosed with COVID-19 or (2) adolescents aged 17-19 who have diagnosed with COVID-19. We will use the interviews to develop and evaluate innovative information tools for parents with COVID-19. These tools will be made widely available using digital and social media platforms.

Approximately 36,000 Canadians and 400,000 Americans undergo heart surgery every year. Many of these individuals will be on blood thinners after surgery to prevent strokes from due to pre-existing atrial fibrillation (AF) or a newly diagnosed AF. The purpose of this study is to establish whether direct oral anticoagulants (DOACs) (ex: Rivaroxaban, Apixaban, etc.) are as safe as vitamin K antagonists (VKAs) (ex: Warfarin) in the first 90 days after heart surgery. The results of this study will impact the treatment of hundreds of thousands of patients in the world every year.

Children diagnosed with arthritis often experience common symptoms like pain, redness, warmth and swelling of the joints. These symptoms can be debilitating and challenge the lives of children that are affected as well as affect their families. It is very important to be able to diagnose these conditions quickly and to provide effective treatments in order to prevent further damage to the joints and affected areas. In order to achieve this, we must understand the underlying causes of these conditions, which are yet to be discovered. The overall goal of our study is to address this gap in treatment approaches as well as support and advance personalized care for all children with juvenile arthritis.

A thoracic aortic aneurysm (TAA) is an abnormal widening in a part of the aorta that passes through the chest causing complications if it tears or ruptures. Aortic size is currently the only tool used for clinical decisions, however, this ‘one size fits all’ approach is imperfect. The purpose of the PREDICT-TAA study is to develop a new, more precise and personalized model to predict TAA growth. Patients in this study will have the stiffness of their arteries assessed by non-invasive instruments and current size of their aortic aneurysm measured by CT or MRI when enrolled. Medical history, blood pressure and a blood sample will also be collected initially. Annual CT or MRI will be conducted for 2 more years to monitor the TAA growth.