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Prebiotic Therapy to Improve Outcomes of Renal Transplant

Kidney Transplant; Complications

An investigator initiated pilot study: two arm, double blind, placebo controlled, randomized, group of approximately 60 patients undergoing a kidney transplant. Participants will be treated with human milk oligosaccharide (HMO) prebiotic versus placebo over 12 weeks from start of the investigational medication date (approximately 3 months) to test whether HMO can improve renal transplant outcomes. Participants will be followed up for 3 months after after they complete the treatment portion of the study. HMO sachets will be administered to determine the safety and efficacy of HMO relative to placebo in improving renal transplant outcomes in patients by reducing delayed graft function and side effects from post transplant therapy.

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Participation Requirements

  • Sex:

    ALL
  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* 18 years of age and over receiving a kidney transplant.

Exclusion Criteria:

* Under 18 years of age
* Inability to give consent
* Usage of probiotics or other prebiotics.
* Have had carcinomas during the last 5 years
* Bowel surgery
* Crohn ́s disease and other conditions.

Study Location

London Health Sciences Centre
London Health Sciences Centre
London, Ontario
Canada

Contact Study Team

Primary Contact

Cadence Baker, MSc

[email protected]
5196858500
Study Sponsored By
London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's
Participants Required
More Information
Study ID: NCT04428190