Prebiotic Therapy to Improve Outcomes of Renal Transplant
Kidney Transplant; ComplicationsAn investigator initiated pilot study: two arm, double blind, placebo controlled, randomized, group of approximately 60 patients undergoing a kidney transplant. Participants will be treated with human milk oligosaccharide (HMO) prebiotic versus placebo over 12 weeks from start of the investigational medication date (approximately 3 months) to test whether HMO can improve renal transplant outcomes. Participants will be followed up for 3 months after after they complete the treatment portion of the study. HMO sachets will be administered to determine the safety and efficacy of HMO relative to placebo in improving renal transplant outcomes in patients by reducing delayed graft function and side effects from post transplant therapy.
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Participation Requirements
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Sex:
ALL -
Eligible Ages:
18 and up
Participation Criteria
Inclusion Criteria:
* 18 years of age and over receiving a kidney transplant.
Exclusion Criteria:
* Under 18 years of age
* Inability to give consent
* Usage of probiotics or other prebiotics.
* Have had carcinomas during the last 5 years
* Bowel surgery
* Crohn ́s disease and other conditions.
Study Location
London Health Sciences Centre
London Health Sciences CentreLondon, Ontario
Canada
Contact Study Team
- Study Sponsored By
- London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's
- Participants Required
- More Information
- Study ID:
NCT04428190