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Using Micro-filaments to Detect "fast Ripples" and Improve the Identification of the Epileptogenic Zone

Epilepsy, Refractory

record fast ripples with novel intracranial electrodes with micro-tetrodes to improve the identification of epileptogenic zone (EZ) and investigate the neuronal circuits underlying brain dynamics associated with epilepsy

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Conditions de participation

  • Sexe:

    ALL

  • Âges admissibles:

    0 and up

Critères de participation

Inclusion Criteria:

* inclusion criteria is determined based on the clinical diagnosis of the refractory epilepsy and the admissibility of the patient for the stereoelectroencephalography (sEEG) procedure

Exclusion Criteria:

* severe psychiatric disorders,
* severe agitation during their crisis
* contraindication for performing an MRI: claustrophobia, a cardiac or neural stimulator, ferromagnetic surgical clips, cochlear implants, intraocular metallic foreign body or in the nervous system,
* contraindication to intracerebral investigation (macro-electrodes): ongoing infection, severe associated pathology (cardiac, pulmonary, renal, hepatic), pregnant or nursing women,
* anti thrombotic ongoing treatment.

Lieu de l'étude

McGill University
McGill University
Montreal, Quebec
Canada

Contactez l'équipe d'étude

Primary Contact

Adrien Peyrache, PhD

[email protected]
514-398-6780
Backup Contact

Birgit Frauscher, PhD, MD

[email protected]
514-398-1911
Étude parrainée par
McGill University
Participants recherchés
Plus d'informations
ID de l'étude: NCT05254730