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Using Micro-filaments to Detect "fast Ripples" and Improve the Identification of the Epileptogenic Zone

Epilepsy, Refractory

record fast ripples with novel intracranial electrodes with micro-tetrodes to improve the identification of epileptogenic zone (EZ) and investigate the neuronal circuits underlying brain dynamics associated with epilepsy

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    0 and up

Participation Criteria

Inclusion Criteria:

* inclusion criteria is determined based on the clinical diagnosis of the refractory epilepsy and the admissibility of the patient for the stereoelectroencephalography (sEEG) procedure

Exclusion Criteria:

* severe psychiatric disorders,
* severe agitation during their crisis
* contraindication for performing an MRI: claustrophobia, a cardiac or neural stimulator, ferromagnetic surgical clips, cochlear implants, intraocular metallic foreign body or in the nervous system,
* contraindication to intracerebral investigation (macro-electrodes): ongoing infection, severe associated pathology (cardiac, pulmonary, renal, hepatic), pregnant or nursing women,
* anti thrombotic ongoing treatment.

Study Location

McGill University
McGill University
Montreal, Quebec
Canada

Contact Study Team

Primary Contact

Adrien Peyrache, PhD

[email protected]
514-398-6780
Backup Contact

Birgit Frauscher, PhD, MD

[email protected]
514-398-1911
Study Sponsored By
McGill University
Participants Required
More Information
Study ID: NCT05254730