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A Study to Assess Real-World Use, Safety, and Effectiveness of Oral Upadacitinib in Adult and Adolescent (>=12 Years Old) Participants With Atopic Dermatitis

Atopic Dermatitis

Atopic dermatitis (AD; also known as atopic eczema) is an inflammatory skin disease. The safety and effectiveness of upadacitinib for AD has been well-documented in previous studies, however, important information is missing on the use patterns and outcomes with upadacitinib in a real-world setting. Therefore, the purpose of this observational study is to help inform real-world usage patterns regarding the safety and effectiveness and duration of response of upadacitinib in adolescent and adult AD participants \>=12 years old in the real-world setting.

Upadacitinib is an approved drug being developed for the treatment of AD. Around 975 adolescent and adult participants who are prescribed upadacitinib for the treatment of AD in routine clinical practice will be enrolled worldwide.

Participants will receive oral upadacitinib as prescribed by their physician. Data from these participants will be collected for approximately 2 years.

There will be no additional burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the course of the study at a hospital or clinic and will be asked to provide additional information by questionnaire at each visit.

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Conditions de participation

  • Sexe:

    ALL
  • Âges admissibles:

    12 and up

Critères de participation

Inclusion Criteria:

* Physician confirmed diagnosis of atopic dermatitis (AD) or atopic eczema at baseline.
* Symptom onset \>=1-year prior to baseline.
* Initiation of upadacitinib treatment for AD is indicated and prescribed per local label.
* The decision to prescribe UPA is made prior to and independently of study participation.
* Medical and medication history available for previous 6 months.
* Participants who can understand the questionnaires, with parental support as required for adolescents.
* Participants who are able to understand and communicate with the investigator and comply with the requirements of the study.
* Participants who are willing and able to participate in the collection of patient-reported data via cloud-based mobile application using a smart device (i.e., tablet).
* Participants who are willing and able to complete the patient-reported questionnaires.

Exclusion Criteria:

- Participants who are currently participating in interventional research (not including non-interventional study, post-marketing observational study, or registry participation).

Lieu de l'étude

Rejuvenation Dermatology - Edmonton Downtown /ID# 240377
Rejuvenation Dermatology - Edmonton Downtown /ID# 240377
Edmonton, Alberta
Canada

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NewLab Clinical Research Inc. /ID# 239600
NewLab Clinical Research Inc. /ID# 239600
St. John's, Newfoundland and Labrador
Canada

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Gordon Sussman Medicine Professional Corporation /ID# 243383
Gordon Sussman Medicine Professional Corporation /ID# 243383
North York, Ontario
Canada

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North York Research Inc /ID# 253191
North York Research Inc /ID# 253191
Toronto, Ontario
Canada

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Clinique D /ID# 239601
Clinique D /ID# 239601
Laval, Quebec
Canada

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Karma Clinical Trials /ID# 239602
Karma Clinical Trials /ID# 239602
St. John's, Newfoundland and Labrador
Canada

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Lynde Institute for Dermatology /ID# 240025
Lynde Institute for Dermatology /ID# 240025
Markham, Ontario
Canada

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Dr. Lyne Giroux Medicine Professional Corporation /ID# 240084
Dr. Lyne Giroux Medicine Professional Corporation /ID# 240084
Sudbury, Ontario
Canada

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Dr Maksym Breslavets Medicine Professional Corporation /ID# 239741
Dr Maksym Breslavets Medicine Professional Corporation /ID# 239741
Whitby, Ontario
Canada

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Clinique de Dermatologie du Haut-Richelieu /ID# 239742
Clinique de Dermatologie du Haut-Richelieu /ID# 239742
St-Jean Sur Le Richelieu, Quebec
Canada

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Winnipeg Clinic /ID# 239603
Winnipeg Clinic /ID# 239603
Winnipeg, Manitoba
Canada

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Dr Melinda Gooderham Medicine Profession /ID# 239745
Dr Melinda Gooderham Medicine Profession /ID# 239745
Cobourg, Ontario
Canada

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JRB Research /ID# 241862
JRB Research /ID# 241862
Ottawa, Ontario
Canada

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Canadian Dermatology Centre /ID# 240585
Canadian Dermatology Centre /ID# 240585
Toronto, Ontario
Canada

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Roula Rassi MD Inc /ID# 252562
Roula Rassi MD Inc /ID# 252562
Laval, Quebec
Canada

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Dr. Irina Turchin PC Inc. /ID# 240358
Dr. Irina Turchin PC Inc. /ID# 240358
Fredericton, New Brunswick
Canada

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Lima's Excellence in Allergy and Dermatology Research Inc /ID# 239854
Lima's Excellence in Allergy and Dermatology Research Inc /ID# 239854
Hamilton, Ontario
Canada

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Dr. Michael Cecchini Medicine Professional Corporation /ID# 239605
Dr. Michael Cecchini Medicine Professional Corporation /ID# 239605
Richmond Hill, Ontario
Canada

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Centricity Research - Toronto Dermatology /ID# 241019
Centricity Research - Toronto Dermatology /ID# 241019
Toronto, Ontario
Canada

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Dre Angelique Gagne-Henley M.D. inc. /ID# 239604
Dre Angelique Gagne-Henley M.D. inc. /ID# 239604
Saint-Jerome, Quebec
Canada

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Étude parrainée par
AbbVie
Participants recherchés
Plus d'informations
ID de l'étude: NCT05081557