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Remission of diabetes a by combining structured exercise with meal replacement: The RESET for Remission Trial

Physical Activity | Type 2 Diabetes | Diet | Exercise

Diabetes remission can be defined as achieving blood glucose levels below the diabetes range, without needing to take any diabetes medication. Shorter-term remission of type 2 diabetes has been achieved through low energy diets. However, the combined effects of low energy diets and supervised exercise on diabetes remission have not been examined. Therefore, the aim of this trial is to optimize remission strategies for early onset diabetes by combining low energy diets with structured exercise training.

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Participation Requirements

  • Sex:

    Any

  • Eligible Ages:

    18 to 45

Participation Criteria

Inclusion Criteria:
• 18 to 45 years of age
• Diagnosis of type 2 diabetes in previous 3 months to 6 years
• HbA1c from 6.0% to 10%
• Excess weight, but stable weight over the previous 6 months
• Able to take part in structured exercise for 24 weeks
• Willing to participate and in a low energy diet which requires abstinence from alcohol
Exclusion Criteria:
• Other forms of diabetes (e.g., type 1 diabetes)
• Insulin therapy
• Currently participating in a weight reduction program in addition to routine care
• Previous bariatric surgery or currently taking weight loss medications
• Previous heart problem, stroke, or amputation
• Pacemaker or implantable defibrillator (ICD)
• Resting blood pressure >150 mmHg systolic and/or > 90 mmHg diastolic

Study Location

University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contact Study Team

Primary Contact

Jordan Rees

[email protected]
780-218-5449
Study Sponsored By
University of Alberta
Participants Required
More Information
Study ID: Pro00101088