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Micro-doses of Physical Activity for COPD

Hypertension | Chronic Obstructive Pulmonary Disease | Cardiovascular Diseases | Endothelial...

Chronic obstructive pulmonary disease (COPD) is a disease of the lungs that makes it hard for people to breath. Those with COPD spend considerably more time sitting and lying and less time performing physical activity than healthy individuals. Those who are the most sedentary have a greater risk of heart and blood vessel disease, which may lead to an early death. This project will investigate the effect of sitting still for 3 hours on blood vessel health in individuals with COPD. It will also investigate whether breaking up the amount of time patients sit with regular short bouts of walking (5 minutes each hour) at a comfortable pace chosen by the patient can have a positive effect on maintaining the health of their blood vessels. It is hypothesized that blood vessel health will be worse after 3 hours of sitting compared to when the sitting is broken up by short bouts of walking.

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Conditions de participation

  • Sexe:

    ALL

  • Âges admissibles:

    0 and up

Critères de participation

Inclusion Criteria:

Non-smoking (\>6 months) patients with stable moderate-to-severe COPD (post bronchodilator forced expired volume in 1 sec/forced vital capacity\<0.7 and \<lower limit of normal, 30%\<Forced Expired Volume in 1 sec\<80% predicted and exacerbation free for \>6 weeks) will be recruited for the study.

Exclusion Criteria:

1. performing structured exercise training (or pulmonary rehabilitation)
2. have a history of deep vein thrombosis
3. are on anticoagulant medication
4. have advanced cardiac or cerebrovascular disease (i.e. heart failure, previous stroke or myocardial infarction)
5. have diabetes
6. have musculoskeletal contraindications that limit their ability to perform physical activity
7. vascular ultrasound measurements cannot be obtained.

Lieu de l'étude

University of British Columbia
University of British Columbia
Kelowna, British Columbia
Canada

Contactez l'équipe d'étude

Primary Contact

Neil Eves, PhD

[email protected]
250-807-9676
Étude parrainée par
University of British Columbia
Participants recherchés
Plus d'informations
ID de l'étude: NCT05553223