Improving health outcomes with kefir.
Diabetes | Prediabetes | Cardiovascular | ImmunityOur study aims to investigate the health benefits of traditional kefir, a fermented dairy drink, especially in metabolic conditions. Unlike commercial kefir, traditional versions with a mix of bacteria and yeast seem more beneficial. In mice, traditional kefir was better than commercial ones in high-fat/cholesterol conditions. Our pilot trial in humans showed promising results, leading us to explore further in people with high blood glucose. We want to see if traditional kefir improves vascular health and immune outcomes in both females and males over 12 weeks.
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Participation Requirements
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Sex:
Any -
Eligible Ages:
24 to 70
Participation Criteria
Inclusion Criteria:
a. Female or male individuals living with T2D or at risk of T2D.
b. Between 24 and 70 years of age.
c. With high blood sugar levels or type 2 diabetes.
Exclusion Criteria:
a. Eating more than 3 servings/week of fermented foods (except cheese) in the last 3 months;
b. Having gastrointestinal disorders or a weakened immune system (e.g., HIV/AIDS, organ transplant);
c. Being pregnant or breastfeeding;
d. Having endocrine disorders (except diabetes) or monogenic dyslipidemia;
e. Taking antibiotics, antifungals, corticosteroids, or immune-suppressing drugs in the last 3 months;
f. Having serious health issues (e.g., kidney/liver disease, cancer, GI surgery, heavy alcohol use);
g. Using a pacemaker or other electronic medical device;
h. Having uncontrolled high blood pressure, cholesterol, or triglycerides (unless stable on meds for 3+ months);
i. Using probiotics or prebiotics recently (needs 4-week washout);
j. Being lactose intolerant or having serious food allergies (e.g., dairy, nuts, soy).
Study Location
University of Alberta
University of AlbertaEdmonton, Alberta
Canada
Contact Study Team
- Study Sponsored By
- University of Alberta
- Participants Required
- More Information
- Study ID:
Pro00139307