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Pericardiotomy in Cardiac Surgery

Atrial Fibrillation | Atrial Flutter | Cardiac Events

PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* Patients greater than or equal to 18 years of age
* Requiring surgical intervention on the proximal aorta, cardiac valves, and/or coronary arteries
* Able to provide informed consent

Exclusion Criteria:

* History of atrial fibrillation or flutter
* Cardiac surgery procedures not included in the inclusion criteria (planned ventricular assistance device, aortic arch, transplantation surgery)
* Prior cardiac surgery requiring opening of the pericardium
* Previous surgical instrumentation of the left pleural cavity
* Patient undergoing minimally invasive cardiac surgery

Study Location

Hamilton Health Sciences
Hamilton Health Sciences
Hamilton, Ontario
Canada

Contact Study Team

Primary Contact

Emilie Belley-Côté, MD, PhD, FRCPC

[email protected]
(905) 527-4322
Study Sponsored By
Population Health Research Institute
Participants Required
More Information
Study ID: NCT06486636