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A Study of the Efficacy of IAMT as an Assessment Tool for Prediction of Progression of Parkinson's Disease

Parkinson Disease

The primary objective of this proposal is to examine the efficacy of Improvised Active Music Therapy (IAMT) sessions as an early novel tool for cognitive and motor assessment for individuals with Parkinson's Disease (PD) in neurological rehabilitation. This will be achieved by identifying subtle variations in how participants play music and correlating these data with mobility and cognitive parameters. The secondary objective is to examine and understand the participants' experience of playing improvised music through post-session interviews as a qualitative measure. We propose to conduct a mixed-method, single-blinded, age-matched group comparison of 25 older adults (= 50 years) with PD and 25 healthy older adults (= 50 years) at the Conrad Institute for Music Therapy Research (CIMTR), Faculty of Music, Wilfrid Laurier University. The CIMTR laboratory contains Musical Instrument Digital Interface (MIDI) equipment/instruments and MATLAB software, which will be used to collect and analyze the music data to compare the two groups. The long-term goal is to build a database of sessions to use Improvised Active Music Therapy (IAMT) as a complementary, reliable, and feasible assessment tool to predict whether older adults with PD will progress to Parkinson's Disease Dementia (PDD) or Dementia with Lewy Bodies (DLB) and distinguish the motor phenotype as Tremor Dominant (PDTD), Mixed (PDM), or Postural Instability and Gait Disturbances (PIGD).

The purpose of this project is to understand the effect of music therapy sessions on cognition and motor skills within the reciprocal improvised music interactions between music therapist and clients. Therefore, the specific objectives are as follows:

1. To examine how physical characteristics of different neurological conditions influence music measures (note frequency, velocity of movement, synchronization, and acquisition of rhythmic complexity).
2. To examine how music measures contribute to cognitive and motor performance.
3. To assess the contributions of individual difference factors such as diagnoses, hand dominance, musical training, music preference, participant's personal experience, and cognitive abilities to music involvement.

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Conditions de participation

  • Sexe:

    ALL

  • Âges admissibles:

    50 and up

Critères de participation

Inclusion Criteria:

* Participants must be at least 50 years old, of any gender and location, and have a clinical diagnosis of Parkinson's Disease (PD).
* Participants should be able to understand and communicate in English.
* Participants should be capable of walking independently for a distance of 80 meters, with or without the use of a gait aid (e.g., walker, cane).
* Participants should be able to sit independently for 30 minutes at a time.
* Participants should be willing to play on a drum-set.
* Participants should NOT be deemed cognitively impaired, as indicated by a score of greater than 24 out of 30 on the Montreal Cognitive Assessment (MOCA).

Exclusion Criteria:

* Individuals who are unable to understand or communicate in English.
* Individuals with any other neurological disorder that has residual motor deficits (e.g., epilepsy, multiple sclerosis).
* Individuals who are using psychotropic medications that can affect motor performance (e.g., neuroleptics/anti-psychotics, anti-convulsants, and benzodiazepines).
* Individuals who have experience as a musician or are currently learning to play an instrument.

Lieu de l'étude

Wilfrid Laurier University
Wilfrid Laurier University
Waterloo, Ontario
Canada

Contactez l'équipe d'étude

Primary Contact

Demian Kogutek, PhD

[email protected]
(548) 889-3623
Étude parrainée par
Wilfrid Laurier University
Participants recherchés
Plus d'informations
ID de l'étude: NCT05971459