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A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of BMS-986393 in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

Multiple Myeloma

The purpose of this study is to establish a safe and tolerable dose of BMS-986393 in combinations with alnuctamab, mezigdomide, and iberdomide in participants with relapsed and/or refractory multiple myeloma (RRMM).

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Conditions de participation

  • Sexe:

    ALL

  • Âges admissibles:

    18 and up

Critères de participation

Inclusion Criteria:

* History of relapsed and/or refractory multiple myeloma (RRMM) treated with at least 3 (Part 1 and Part 2) or at least 1 but not greater than 3 prior anti-myeloma treatment regimens (Part 2)
* Measurable multiple myeloma (MM)
* Eastern Cooperative Oncology Group performance status of 0-1

Exclusion Criteria:

* Condition that confounds the ability to interpret data from the study
* Known active or history of central nervous system (CNS) involvement of MM

Note: Other protocol-defined inclusion/exclusion criteria apply

Lieu de l'étude

Tom Baker Cancer Center
Tom Baker Cancer Center
Calgary, Alberta
Canada

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Primary Contact

Nizar Bahlis, Site 0013

4032202801
Local Institution - 0024
Local Institution - 0024
Toronto, Ontario
Canada

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Primary Contact

Site 0024

Étude parrainée par
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Participants recherchés
Plus d'informations
ID de l'étude: NCT06121843