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An Innovative Master Platform for Clinical Trials in Mood Disorders

Mood Disorders | Depressive Disorder | Bipolar and Related Disorders

Mood disorders such as depression and bipolar disorder affect over 350 million people around the world. While several effective treatments exist, it is often difficult to match the right treatment to an individual person. Repeated efforts to find the right treatment contribute to poor functioning, low quality of life, and prolongs the time it takes to get well. Most areas of medicine are able to use 'biomarkers' or clinical tests, blood tests, or imaging to help diagnose and treat illness. The search for biomarkers in mood disorders is advancing, but one roadblock to progress is the lack of large, standardized studies of mood disorders that are needed to accurately identify biomarkers. The aim of the ENABLE platform is to provide the Canadian neuroscience community a standardized way of collecting biomarker data from individuals with a range of mood disorders symptoms. In addition, this 'master clinical trial platform' framework will provide a pool of participants who can be recruited into biomarker-based clinical trials.

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Conditions de participation

  • Sexe:

    ALL

  • Âges admissibles:

    16 and up

Critères de participation

Inclusion Criteria

Patients:

1. 16 years of age or older.
2. Meet criteria for bipolar or depressive disorders as defined by DSM-5.
3. Fluency in English, sufficient to complete the interviews and self-report questionnaires.

Inclusion Criteria

Healthy Comparison (HC) Participants:

1. 16 years of age or older.
2. No history of psychiatric disorders (according to DSM-5) or significant unstable medical conditions.
3. Fluency in English, sufficient to complete the interviews and self-report questionnaires.

Lieu de l'étude

University of British Columbia
University of British Columbia
Vancouver, British Columbia
Canada

Contactez l'équipe d'étude

Backup Contact

Raymond W Lam, MD

Primary Contact

Sara Lee

[email protected]
604 822 0332
University of Ottawa
University of Ottawa
Ottawa, Ontario
Canada

Contactez l'équipe d'étude

Backup Contact

Pierre Blier, MD, PhD

Primary Contact

Yamini Singh

[email protected]
613.722.6521
University of Calgary
University of Calgary
Calgary, Alberta
Canada

Contactez l'équipe d'étude

Primary Contact

Alexandra Du

[email protected]
403-220-6533
Backup Contact

Valerie H Taylor, MD, PhD

Queen's University
Queen's University
Kingston, Ontario
Canada

Contactez l'équipe d'étude

Primary Contact

Rida Khan

[email protected]
613-544-4900
Backup Contact

Roumen Milev, MD, PhD

McMaster University
McMaster University
Hamilton, Ontario
Canada

Contactez l'équipe d'étude

Backup Contact

Benicio N Frey, MD, PhD

Primary Contact

Saba Khoshroo, MSc

[email protected]
905 522 1155
Centre for Addiction and Mental Health
Centre for Addiction and Mental Health
Toronto, Ontario
Canada

Contactez l'équipe d'étude

Backup Contact

Lena Quilty, PhD

Primary Contact

Amy Zhang

[email protected]
416-535-8501
Nova Scotia Health Authority
Nova Scotia Health Authority
Halifax, Nova Scotia
Canada

Contactez l'équipe d'étude

Primary Contact

Shizza Hassan

[email protected]
902-473-1782
Backup Contact

Rudolf Uher, MD

University Health Network
University Health Network
Toronto, Ontario
Canada

Contactez l'équipe d'étude

Primary Contact

Marianne Bautista

[email protected]
(416) 603-5800
Backup Contact

Joshua Rosenblat, MD

Étude parrainée par
St. Joseph's Healthcare Hamilton
Participants recherchés
Plus d'informations
ID de l'étude: NCT06408012