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Fecal Immunochemical Test for Post-polypectomy Surveillance to Reduce Unnecessary eNdoscopy

Colorectal Neoplasms

This is an observational study in a clinical setting to estimate the prevalence of advanced colorectal neoplasia (ACN) at colonoscopy in those with a history of low or high risk polyps or a family history of CRC/polyps and to verify the test performance characteristics of FIT in these populations. Using this information, a risk prediction model will be developed to help guide the choice between FIT and colonoscopy in the ongoing surveillance or screening of patients.

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Conditions de participation

  • Sexe:

    ALL
  • Âges admissibles:

    18 to 74

Critères de participation

Inclusion Criteria:

1. Men or women age ≤ 74 years of age.
2. At least one risk factor for CRC that would generally lead to colonoscopy screening:

1. Personal history of low risk polyps
2. Personal history of high risk polyps
3. Family history of CRC or polyps

Exclusion Criteria:

1. Known acromegaly, cystic fibrosis or high risk profession (firefighter)
2. Referred for colonoscopy due to a positive fecal immunochemical test or CT colonography
3. Known or suspected gene carrier for a familial cancer syndrome.
4. Does not meet medical criteria for colonoscopy at the CCSC.
5. Colonoscopy within the previous 30 months
6. Unable to provide written informed consent or complete questionnaires due to language barrier or other reasons.

Lieu de l'étude

Forzani & Macphail Colon Cancer Screening Centre, University of Calgary
Forzani & Macphail Colon Cancer Screening Centre, University of Calgary
Calgary, Alberta
Canada

Contactez l'équipe d'étude

Primary Contact

Robert Hilsden

[email protected]
1-403-592-5089
Backup Contact

Susanna Town

[email protected]
1-403-592-5052
Étude parrainée par
University of Calgary
Participants recherchés
Plus d'informations
ID de l'étude: NCT05396560