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IVIM & OLINK in Sarcoma

Soft Tissue Sarcoma

The hypoxia \> metastasis axis suggests that a DWI-based biomarker of hypoxia incorporating IVIM may be able to predict metastasis in STS patients, ultimately enabling stratification for personalized treatments at the time of diagnostic (MR) imaging, without adding an excessive burden to the patient or clinical workflow (typical DWI/IVIM sequences can be acquired acquired in approximately 5 minutes).

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* Age ≥ 18 years
* Ability to understand and the willingness to sign a written informed consent document
* Grade 2 or 3 soft tissue sarcoma greater than 5 cm in largest dimension
* Recommendation from the sarcoma team that the patient should undergo neo-adjuvant radiotherapy prior to surgical resection

Exclusion Criteria:

* Contraindication to MRI scan as per current institutional guidelines

Study Location

University Health Network
University Health Network
Toronto, Ontario
Canada

Contact Study Team

Primary Contact

David Shultz, MD

[email protected]
416 946 4501
Study Sponsored By
University Health Network, Toronto
Participants Required
More Information
Study ID: NCT05950594