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Virtual home-based physical pre-habilitation in kidney transplant candidates: a pilot RCT.

Kidney Transplant Candidates

This pilot RCT is critical to test acceptability, assess logistics, optimize the design, and build the capacities for a full-scale RCT. Our multicenter pilot randomized controlled trial (RCT) will address the following research question: is it feasible to conduct a full-scale multicenter RCT to assess the comparative-effectiveness of a virtual home-based pre-habilitation versus usual care for kidney transplant candidates?

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Conditions de participation

  • Sexe:

    Any
  • Âges admissibles:

    18 and up

Critères de participation

Inclusion Criteria:
•individuals with end stage kidney disease (aged ≥18 years), classified as pre-frail, frail or very frail and who are accepted or in the process of being accepted to enter in the deceased or living donor KT waiting list of the MUHC, CHUM or UAH for first-time transplantation or re-transplantation.
•English or French speakers
•is technologically capable of connecting (either independently or through household members/next-of-kin) with an online videoconferencing platform through an e-mail invitation (Patients who do not have access to internet will borrow a tablet with internet for the period of the study)
Exclusion Criteria:
Individuals
•are classified as robust (0 points) on their Fried’s frailty phenotype score
•are participating in a structured exercise program (hospital-based or home-based or another trial)
•are waiting for kidney-pancreas or kidney-liver transplant as those have much longer waiting time
•are hospitalized for any reason during the assessment for eligibility
•have a cPRA (calculated panel reactive antibodies) >95% and
•are on the highly sensitized exchange program and expected to have a prolonged waiting times on the waiting list
•are expected to have a transplant before the end of the 12 week-intervention (e.g., individuals who will receive an organ from a living donor or are type A blood
•have pre-existing or newly identified significant cognitive impairment have pre-existing or newly identified cardiac, musculoskeletal, neuropathy or neurological condition that might affect their exercise performance or otherwise render rehabilitation participation unsafe Recruitment Strategy and Randomization

Lieu de l'étude

University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contactez l'équipe d'étude

Primary Contact

Stephanie Thompson

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780-492-3255
Primary Contact

Lalantha Coonghe

[email protected]
7808076197
Primary Contact

Rachelle Davis

[email protected]
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Étude parrainée par
University of Alberta
Participants recherchés
Plus d'informations
ID de l'étude: Pro00136026