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Potassium (K) Handling in Advanced Chronic Kidney Disease (K-HANDLE CKD)

Diet | Kidney

This study aims to understand how different types of potassium from food affect people with advanced chronic kidney disease (CKD). Potassium is a nutrient found in many foods, but when kidney function is reduced, managing potassium levels becomes challenging. We will compare the effects of potassium from minimally processed foods, like fresh fruits and vegetables, to potassium from ultra-processed foods, such as packaged or fast foods. The goal is to determine which sources of potassium are safer for CKD patients and to improve dietary guidelines, allowing for healthier and more enjoyable food choices without increasing health risks.

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Conditions de participation

  • Sexe:

    Female, Male

  • Âges admissibles:

    18 and up

Critères de participation

Inclusion Criteria:
Adults aged 18 years or older.
Living with advanced chronic kidney disease (CKD) in stages 3B, 4, or 5 but not on dialysis or planning to start dialysis within the next 6 months.
Both men and women can participate.
Able to follow a specific diet and attend in-person visits.
Exclusion Criteria:
Women who are pregnant or breastfeeding; People with strict diets, such as vegetarians or vegans, that would prevent them from following the study meals; Those expected to start dialysis or receive a kidney transplant within six months; Acute kidney injury in the last 3 months; People with a high risk of kidney failure; History of kidney transplant or active kidney inflammation; Recent heart attack or stroke; Active cancer or certain digestive system conditions; Very low or very high body weight; Severe heart failure; uncontrolled diabetes; chronic stomach issues; Recent hospital admission to the ICU; recent major surgery; or active autoimmune disease; Significant mental health conditions that may interfere with study participation; People taking certain medications, such as: immunosuppressants, potassium binders, lithium, medications that affect bowel movements, more than two medications that reduce the body’s ability to excrete potassium. High potassium levels on three or more occasions in the last year; Genetic or unique health conditions affecting potassium levels; Unstable blood pressure or fluid levels that require active management; Documented difficulties following prescribed treatments; Dependence on tube feeding or intravenous nutrition; Known allergies to any ingredients in the study meals.

Lieu de l'étude

University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contactez l'équipe d'étude

Primary Contact

Jenneffer Rayane

[email protected]
780-492-9506
Étude parrainée par
University of Alberta
Participants recherchés
Plus d'informations
ID de l'étude: Pro00139586