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Evaluating the Safety and Efficacy of Geniculate Artery Embolization for the Treatment of Knee Osteoarthritis Associated Pain

Osteoarthritis of the Knee | Arthritis | Knee Pain | Orthopedics

The goal of this study is to check the safety and effectiveness of blocking small abnormal blood vessels to the knee for patients with knee osteoarthritis. The goal is to decrease pain and increase quality of life.

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Participation Requirements

  • Sex:

    Male, Female, Intersex

  • Eligible Ages:

    40 to 85

Participation Criteria

Inclusion Criteria:
1. Moderate to severe symptoms (to be assessed by visual analog scale prior to study enrolment)
2. Pain present for 3 months or greater despite conservative therapy (including medical therapy, physiotherapy, intra-articular cortisone or viscosupplement injection).
3. Age > 40 years
4. Radiographs demonstrating knee osteoarthritis on same side as pain
5. Patient not a surgical candidate or declines surgical management

Exclusion Criteria:
1. Radiographically severe knee osteoarthritis
2. Severe non-knee related lower limb pain
3. Local infection and inflammatory arthritis.
4. Malignancy
5. Previous knee surgery
6. Bleeding risk/bleeding disorder
7. Known chronic renal failure
8. Patient confined to bed or chair for >50% of the time
9. Patient weight > 300 lbs
10. Patient unable for follow up

Study Location

University of Calgary
University of Calgary
Calgary, Alberta
Canada

Contact Study Team

Study Sponsored By
University of Calgary
Participants Required
More Information
Study ID: REB21-0641