BreathinG-induced Myocardial and Cerebral Perfusion in Anxiety Disorders

Conditions de participation

• Sexe:

  ALL

• Âges admissibles:

  18 to 55

Critères de participation

Inclusion Criteria:

Patient population:

Age 18-55,

* Confirmation of an anxiety disorder as identified by the PSWQ,
* No known, current or history, of significant medical conditions that may affect or directly involve the neurological, cardiovascular or respiratory system (except anxiety and depression)
* Non-smoker

Healthy Volunteers:

* Age 18-55
* No known, current or history, of significant medical conditions that may affect or directly involve the neurological, cardiovascular or respiratory system
* Non-smoker

Exclusion Criteria:

* General MRI contraindications: pacemakers, defibrillating wires, implanted defibrillators, intracranial aneurysm clips, metallic foreign bodies in the eyes, pregnancy
* History of significant neurological disease or illness that is not anxiety (e.g. Dementia, stroke)
* Hemodynamically unstable conditions
* Significant or uncontrolled arrhythmias
* Severe pulmonary disease
* Recent (\<90 days) myocardial infarction
* Recent (\<90 days) surgery or coronary intervention
* Consumption of caffeine (caffeinated beverages, coffee, tea, cocoa, chocolate) within 12h of the exam
* Use of benzodiazepines or other short-acting anxiety medications (\<1 day)