Epinephrine Dose: Optimal Versus Standard Evaluation Trial
Sudden Cardiac Arrest | Ventricular Fibrillation | Cardiac Arrest, Out-Of-Hospital | Ventricular Tachycardia-PulselessThe objective of this randomized controlled trial is to evaluate the effectiveness of a low cumulative dose of epinephrine compared to a standard cumulative dose of epinephrine during resuscitation from ventricular fibrillation (VF) or ventricular tachycardia (VT) in adult out-of-hospital cardiac arrest (OHCA) patients.
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Conditions de participation
-
Sexe:
ALL -
Âges admissibles:
18 and up
Critères de participation
Inclusion Criteria:
* Out-of-hospital cardiac arrest treated by paramedics
* Initial recorded cardiac rhythm of VF or pulseless VT, or, AED shock on first analysis administered or witnessed by EMS (paramedic or fire)
* Established intravenous vascular access
Exclusion Criteria:
* Known or apparent age \<18 years
* Initial recorded cardiac rhythm of VF or pulseless VT, or, AED shock on first analysis administered or confirmed by paramedics
* Cardiac arrest due to an obvious non-cardiac primary cause (e.g. blunt or penetrating trauma, exsanguination, burns, drug overdose, drowning, anaphylaxis, sudden asphyxiation, etc.)
* Administration of intramuscular, endotracheal tube, or intraosseous epinephrine
* Prisoners or persons in police custody
* Known allergy or sensitivity to epinephrine
Lieu de l'étude
Ottawa Paramedic Services
Ottawa Paramedic ServicesOttawa, Ontario
Canada
Contactez l'équipe d'étude
British Columbia Emergency Health Services (BCEHS)
British Columbia Emergency Health Services (BCEHS)Victoria, British Columbia
Canada
Contactez l'équipe d'étude
Halton Region Paramedic Services
Halton Region Paramedic ServicesHalton, Ontario
Canada
Contactez l'équipe d'étude
- Étude parrainée par
- Unity Health Toronto
- Participants recherchés
- Plus d'informations
- ID de l'étude:
NCT03826524