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Fiber and metformin therapy in adolescents with obesity and insulin resistance

Obesity | Diabetes | Insulin Resistance | Metformin

The purpose of this study is to evaluate the effects of a fiber supplement and metformin alone and in combination, over 6 months, on metabolism and inflammation through changes in the gut microbes in adolescents with obesity, insulin resistance and family history of type 2 diabetes.
Our study will provide information about effective strategies for the prevention and treatment of such conditions. Early detection and therapy might help control weight gain and prevent type 2 diabetes in adulthood.

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Conditions de participation

  • Sexe:

    Female, Male

  • Âges admissibles:

    12 to 18

Critères de participation

Inclusion Criteria:
* Age 12-18 years.
* Obesity and insulin resistance.
* Family history of type 2 diabetes.
Exclusion Criteria:
* Current use of insulin or diagnosis of type 2 diabetes.
* History of chronic disease such as inflammatory bowel disease, chronic severe liver or kidney disease, or severe neurological disorders.
* Pregnancy and breastfeeding.
*Known allergy to corn, or to any of the ingredients in the study products.

Lieu de l'étude

University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contactez l'équipe d'étude

Primary Contact

Metfiber study research team

[email protected]
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Étude parrainée par
University of Alberta
Participants recherchés
Plus d'informations
ID de l'étude: Pro00100067