INhaled Salbutamol vs Placebo for the Treatment of Acute IgE-mediated Abdominal Pain From Allergic Food REactions
IgE-mediated Abdominal PainThe goal of this study is to assess the efficacy of inhaled salbutamol to treat abdominal pain during food allergic reactions.
Patients experiencing abominal pain as a result of a food allergic reaction during a food challenge in the allergy clinic will be invited to participate to the study.
They will receive either 8 puffs of salbutamol (asthma inhaler) or 8 puffs of a placebo inhaler.
The abdominal pain will then be followed using a numeric scale to see if patients receiving the medication experienced a faster improvement compared to those receiving the placebo.
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Conditions de participation
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Sexe:
ALL -
Âges admissibles:
6 to 55
Critères de participation
Inclusion Criteria:
* Subjects aged between 6 to 55 years old.
* Undergoing an oral food challenge or an oral immunotherapy up-dosing visit for the diagnosis or treatment of an IgE-mediated food allergy.
* Previous confirmation of the food allergy by either skin prick tests (SPT) or serum specific IgE;
* Able to express the intensity of their pain using the NRS-11;
* Willing to comply with all study requirements.
Exclusion Criteria:
* Previous adverse reactions to salbutamol;
* Known hypersensitivity to salbutamol or placebo or any of their components;
* Any condition that could be considered a relative contra-indication to the use of salbutamol according to the investigator (e.g. patient with a history of hyperglycemia, arrhythmia or hypokalemia);
* Patients receiving beta-blockers or a daily / long-acting beta agonists;
* Patients needing to pass an anti-doping test for high-level sport in the following 24h.
Lieu de l'étude
CHU Sainte-Justine
CHU Sainte-JustineMontréal, Quebec
Canada
Contactez l'équipe d'étude
- Étude parrainée par
- St. Justine's Hospital
- Participants recherchés
- Plus d'informations
- ID de l'étude:
NCT05653024