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Psychosocial, Cognitive, and Behavioral Consequences of Sleep-disordered Breathing After SCI

Spinal Cord Injuries | Sleep Apnea

This clinical trial will examine the efficacy of continuous positive airway pressure (CPAP) therapy in improving psychosocial, neurocognitive and behavioral consequences of moderate-to-severe sleep-related breathing disorders (SRBDs) in people living with spinal cord injury (SCI).

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* English-speaking adults 18 years of age or older
* Have traumatic cervical/thoracic (injury level at C5 to T10), severe or moderate (AIS A, B, or C) SCI who were not diagnosed with a sleep disorder prior to the injury.
* At least 2 months after injury
* Clinical warning symptoms and/or signs for SRBDs

Exclusion Criteria:

* Patients with a non-traumatic spinal cord disease at risk for neurologic progression
* Concomitant diseases of the central nervous system
* Preinjury chronic pain
* Psychiatric disorders that may prevent the participant to be compliant to the study protocol requirements
* Neuromuscular diseases
* Current substance misuse
* History of primary hypersomnia
* Hypothyroidism
* Moderate or severe iron deficiency anemia
* Active infection
* Kidney failure
* Epilepsy
* Chronic fatigue syndrome
* Vitamin B12 deficiency

Study Location

Lyndhurst Centre, KITE - TRI UHN
Lyndhurst Centre, KITE - TRI UHN
Toronto, Ontario
Canada

Contact Study Team

Primary Contact

Mitsue Aibe, MD

[email protected]
416-597-3422
Study Sponsored By
University Health Network, Toronto
Participants Required
More Information
Study ID: NCT04007380