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Assessment of Stroke Volume and Cardiac Output in Response to Varying Heart Rates

Vasovagal Syncope

The investigators will seek to determine the effects of different heart rates on both stroke volume and cardiac output using non-invasive hemodynamic assessments. In order to safely manipulate the HR, the investigators will study patients with permanent pacemakers in whom heart rate manipulation can be done in a safe and non-invasive manner.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 to 70

Participation Criteria

Inclusion Criteria:

* Age 18-70 years (inclusive)
* Implanted permanent pacemaker or implanted defibrillator capable of atrial and ventricular pacing
* LV ejection fraction \>50%

Exclusion Criteria:

* Unable or unwilling to provide informed consent
* Clinical need for a cardiac resynchronization device

Study Location

University of Calgary
University of Calgary
Calgary, Alberta
Canada

Contact Study Team

Backup Contact

Robert S Sheldon, MD, PhD

[email protected]
403-220-8191
Primary Contact

Satish R Raj, MD, MSCI

[email protected]
403-210-6152
Study Sponsored By
University of Calgary
Participants Required
More Information
Study ID: NCT03446326