Parkinson's Disease Biomarker Study
REM Sleep Behavior Disorder | Parkinson Disease, IdiopathicThe primary objective of this study is to determine whether data acquired from a remote monitoring approach can reliably identify and track motor symptoms in prodromal PD and clinical PD.
The study is a one-year longitudinal biomarker study recruiting idiopathic RBD patients, Parkinson's Disease patient and healthy controls. All participants receive a smartphone with the Roche PD Mobile Application, complete a number of active tests daily and their movements will be remotely monitored. Participants will undergo additional neurological exams and DaT-SPECT and MRI imaging in the study.
A second objective of this study will be to validate an immunohistochemistry skin biopsy assay for the detection of pathological alpha-synuclein diagnostic of PD, in the peripheral nerves of the skin.
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Conditions de participation
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Sexe:
ALL -
Âges admissibles:
40 and up
Critères de participation
Inclusion Criteria:
* signed consent form, male or female over age 40, ability to follow protocol, additional group-specific inclusion criteria
Exclusion Criteria:
* participation in interventional clinical study within 3 months of screening, moderate to severe depression in judgement of the investigator, any concomitant disease, condition or treatment which may interfer with the conduct of study (determined by investigator), additional group-specific exclusion criteria
Lieu de l'étude
Pacific Parkinson's Research Centre
Pacific Parkinson's Research CentreVancouver, British Columbia
Canada
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The Neuro
The NeuroMontreal, Quebec
Canada
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Centre hospitalier de l'Université de Montréal (CHUM)
Centre hospitalier de l'Université de Montréal (CHUM)Montreal, Quebec
Canada
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- Étude parrainée par
- McGill University
- Participants recherchés
- Plus d'informations
- ID de l'étude:
NCT06812702