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Exercise Intensity Matters in Stroke Rehabilitation

Stroke

The main objective of this multi-site project is to compare the effects of 12 weeks of HIIT vs. MICT on brain plasticity. The effects of HIIT vs. MICT on cardiovascular health, psychosocial predictors of physical activity and motor function will also be compared. HIIT and MICT will be delivered through a whole-body exercise paradigm using a recumbent stepper that requires arm and leg forces. Outcomes will be assessed at baseline (T0, 0 weeks), at the end of the intervention (T1, 12 weeks) and at 8-week follow-up (T2, 20 weeks).

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    40 to 80

Participation Criteria

Inclusion Criteria:

* 6-60 months following first-ever, single stroke confirmed by MRI/CT
* Living in the community and able to independently walk at least 10 meters (assistive devices permitted, as this is representative of many people who regain some walking ability following stroke but commonly with some adaptation)
* Montreal Cognitive Assessment score \>20 (individuals with this score are capable to follow exercise instructions)

Exclusion Criteria:

* Significant disability as determined by modified Rankin scale score \<2
* Stroke of non-cardiogenic origin or tumor
* Actively engaged in stroke rehabilitation services or a structured exercise program besides the one provided in the study
* Class C or D American Heart Association Risk Criteria
* Other neurological or musculoskeletal co-morbidities that preclude exercise participation
* Pain which is worsened with exercise
* Cognitive, communication, or behavioral issues that would limit safe exercise participation
* Contraindications to transcranial magnetic stimulation.

Study Location

Jewish Rehabiliation Hospital
Jewish Rehabiliation Hospital
Laval, Quebec
Canada

Contact Study Team

Backup Contact

Jean-Francois Nepveu, MSc

450-688-9550
Primary Contact

Marc Roig, PhD

[email protected]
450-688-9550
Ontario Central South Stroke Network
Ontario Central South Stroke Network
Hamilton, Ontario
Canada

Contact Study Team

Primary Contact

Ada Tang, PhD

[email protected]
905-525-9140
Backup Contact

Jennifer Crozier, MSc

[email protected]
Study Sponsored By
McGill University
Participants Required
More Information
Study ID: NCT03614585