National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children
Adverse Drug Reaction (ADR)The purpose of the study is (1) to identify and collect samples from children and adults who take drugs and have adverse drug reactions AND children and adults who take drugs and do not experience any adverse drug effects; (2) to determine if genetic differences between the two groups contribute to causing the adverse drug reactions; and (3) to develop patient specific drug dosing guidelines to prevent future adverse drug reactions. We also wish to compare the use of prescription drugs, medical and hospital services and vital statistics between BC participants who experience adverse drug reactions and those who do not.
Study hypothesis: Genetic differences may contribute to patients' response to drugs and may be responsible for adverse drug reactions.
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Conditions de participation
-
Sexe:
ALL -
Âges admissibles:
0 and up
Critères de participation
Inclusion Criteria:
* Children under 19 years who have taken drugs.
* Biological parents of children who have had an ADR.
* Patients/parents who speak and understand English (except in Quebec).
* Adults (for validation of findings in children)
Lieu de l'étude
Children's and Women's Health Centre of British Columbia
Children's and Women's Health Centre of British ColumbiaVancouver, British Columbia
Canada
Contactez l'équipe d'étude
- Étude parrainée par
- University of British Columbia
- Participants recherchés
- Plus d'informations
- ID de l'étude:
NCT00414115