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"The MEMORI Study" – Imaging memory and cognition in dementia research.

Cognition | Memory Disorders

This study wants to find a better way to identify people who have early signs of memory loss, trouble with thinking and decision-making, difficulty paying attention, and slower processing speed. The study enrolls community dwelling older adults for assessments of cognition, behaviour, function, quality of life, and caregiver stress, in association with biomarkers, at 6, 12 or 18 month intervals. Participants attend with a study partner, and at each visit are given a series of questionnaires and tests (the study partner will only be asked to answer the questionnaires). The overall visit is ~1.5 to -2.5 hours in duration. Non-invasive brain imaging (electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) will be used to record brain activity patterns. We will compare these patterns in healthy people, people with mild memory problems, and people with mild to moderate dementia. By understanding these patterns, we will create a way to detect memory problems sooner so people can get the proper treatment and support.

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Conditions de participation

  • Sexe:

    Male, Female, Intersex

  • Âges admissibles:

    55 and up

Critères de participation

Inclusion Criteria:
1. Age 55 or older with normal cognition, subjective cognitive decline, mild cognitive impairment, mild AD dementia, or moderate AD dementia.
2. Study partner available who has known the participant for 5 years
Exclusion Criteria:
1. Developmental disorders and neuropsychiatric conditions that would affect testing (e.g., autism, Huntington's disease, schizophrenia, bipolar disorder)

2. Unable to provide informed consent

3. Not fluent in English

Lieu de l'étude

University of Calgary
University of Calgary
Calgary, Alberta
Canada

Contactez l'équipe d'étude

Étude parrainée par
University of Calgary
Participants recherchés
Plus d'informations
ID de l'étude: REB23-0256