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Programmed Intermittent Epidural Bolus Versus Continuous Infusion in Labour Analgesia

Labor Pain

This study aims to establish if programmed intermittent epidural bolus combined to patient controlled analgesia in labour analgesia will lower the hourly bupivacaine consumption when compared to continuous infusion combined with patient controlled analgesia. The investigators' hypothesis is that the use of programmed intermittent epidural bolus will lower the hourly bupivacaine consumption.

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Participation Requirements

  • Sex:

    FEMALE

  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* Pregnant nulliparous or multiparous woman in labour
* Age ≥18 years
* Obtained consent for epidural analgesia
* ASA classification I-II-III
* Early labour (cervical dilation ≤6cm)

Exclusion Criteria:

* Pregnancy-related comorbidities (preeclampsia, eclampsia, gestational diabetes, large for gestational age fetus)
* Prematurity (\<36 weeks of gestation)
* Multiple gestation
* Fentanyl allergy or hypersensitivity
* Patient unable to understand the PCEA
* Fetal breech position
* Maternal cardiac pathology and contraindication to Valsalva manoeuvre
* Patient with a pain visual analog scale (VAS) not ≤1/10 20 minutes after the anesthesiologist's initial bolus
* Intrathecal catheter or intravascular catheter
* Accidental dural puncture
* Patient refusal
* Patient with a history of chronic pain (pain lasting more than 3 months) or fibromyalgia

Study Location

CHUS
CHUS
Sherbrooke, Quebec
Canada

Contact Study Team

Primary Contact

Genevieve Rivard, FRCPC

[email protected]
8195651502
Backup Contact

Isabelle Caron

[email protected]
Study Sponsored By
Université de Sherbrooke
Participants Required
More Information
Study ID: NCT03730753