Skip to content

Fecal transplant for primary Clostridioides difficile infection.

Fecal Transplant | Clostridioides Difficile Infection | C. Diff Infection

Clostridioides difficile can cause diarrhea, abdominal pain and fever. It is most often caused by antibiotic use, which can kill many beneficial bacteria in the gut. The usual treatment is more antibiotics, which only helps in some cases. Fecal microbiota transplantation (FMT) involves transferring stool from a healthy donor to a sick patient. It is used to correct the imbalance in gut bacteria from antibiotics and has been successfully used in patients where infection keeps coming back. This study will compare 2 treatments in patients who have C diff infection (CDI) for the first time within the previous 6 months (primary CDI): vancomycin for 10 days or vancomycin 5 days followed by freeze-dried FMT capsules.

null

Conditions de participation

  • Sexe:

    Female, Male

  • Âges admissibles:

    18 to 90

Critères de participation

Inclusion Criteria:
Patients over the age of 18 who have Clostridioides difficile infection (CDI) for the first time within the previous 6 months (primary CDI).
Exclusion Criteria:
Patients whose CDI is severe requiring hospitalization or surgery.
Patients with chronic diarrheal illness, such as irritable bowel syndrome or inflammatory bowel disease.
Patients of childbearing age who do not want to use some form of contraception.

Lieu de l'étude

University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contactez l'équipe d'étude

Étude parrainée par
University of Alberta
Participants recherchés
Plus d'informations
ID de l'étude: Pro00128608