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KETO-IM Study

Diabetes | Prediabetes | Cardiovascular | Immunity

The ketogenic diet (KETO) is popular for weight loss and is gaining interest as a treatment for type 2 diabetes (T2D) because it is believed to help manage blood glucose and weight. However, KETO is often high in saturated fats (SFA), which may increase cholesterol and other cardiovascular (CVD) risk factors, such as inflammatory profile. Substituting a heart-healthy oil for SFA may improve these outcomes. The purpose of our study is to investigate the health beneficial effects of a healthy KETO diet supplemented with Canola oil, compared to a traditional Keto Diet and low-fat diet in adults at high risk of type 2 diabetes. Participants will be randomized to one of these three diets and will receive nutrition counselling during 6 months.

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Participation Requirements

  • Sex:

    Any
  • Eligible Ages:

    18 to 70

Participation Criteria

Inclusion Criteria:
Female or male living with overweight or obesity; Between 18 and 70 years of age; With slightly elevated blood sugar levels or type 2 diabetes.
Exclusion Criteria:
Pregnant women, people on dialysis or recommended to follow a low-protein diet, familial hypercholesterolemia or hypertriglyceridemia, transitioning trans-gender. Patients with history of diabetic ketoacidosis.

Study Location

University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contact Study Team

Primary Contact

Paulina Blanco

[email protected]
780-492-9506
Study Sponsored By
University of Alberta
Participants Required
More Information
Study ID: Pro00123687