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Fitness to Aid the Brain and Cognitive Skills

Cognitive Impairment | Pediatric Brain Tumor

The study will assess the feasibility of a pilot clinical trial of community-led aerobic exercise training for paediatric brain tumour survivors (PBTS) and the feasibility of a web-based platform to deliver this exercise training. It is hypothesized that 12 weeks of community-led exercise training will be feasible for PBTS and the web-based platform will be feasible to deliver exercise training by community-based instructors.

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Participation Requirements

  • Sex:

    ALL
  • Eligible Ages:

    6 to 18

Participation Criteria

Inclusion Criteria:

1. Between 6 years and 17 years and 11 months of age at time of enrollment
2. Diagnosed with a brain tumour
3. 1 to 15 years between diagnosis and time of study enrollment
4. Medically stable (i.e. must be in remission) as determined by a permanent SickKids staff Neuro-Oncologist
5. Either declare English as their native language or have at least two years of schooling in English at the time of their first assessment
6. Have a parent or legal guardian willing to complete the Health and Quality of Life measures
7. Informed consent (and assent, where applicable) will be obtained from the participants and/or their legal guardians

Exclusion Criteria:

1. Any condition or diagnosis, that could in the opinion of the Principal Investigator or delegate, interfere with the participant's ability to comply with study instructions, might confound the interpretation of the study results, or put the participant at risk
2. Diagnosed with a neurodevelopmental or neurological disorder, cerebral palsy, developmental delay or learning disability prior to initial brain tumour diagnosis that would preclude safe participation
3. Receiving palliative care
4. Require sedation for neuroimaging
5. Have ferrous metal implants (i.e. cochlear implant, braces, etc.)
6. Have a programmable shunt
7. Pregnant
8. Completed any prior cognitive rehabilitation intervention within three months of enrollment

Study Location

The Hospital for Sick Children
The Hospital for Sick Children
Toronto, Ontario
Canada

Contact Study Team

Primary Contact

Donald J Mabbott, Ph.D.

[email protected]
416-813-7654
Backup Contact

Cynthia de Medeiros, M. Sc.

[email protected]
416-813-7396
Study Sponsored By
The Hospital for Sick Children
Participants Required
More Information
Study ID: NCT05367076