Skip to content

Comparison between invasive and non-invasive measures of sympathetic nerve activity during autonomic function tests in adults

Autonomic Nervous System

To study, evaluate, and compare invasive and non-invasive sympathetic nerve activity (fight or flight response) measurements during tests of breathing, a handgrip test (pushing against force), and a cold pressor test (hand in ice water)

null

Participation Requirements

  • Sex:

    Male, Female, Intersex

  • Eligible Ages:

    18 to 85

Participation Criteria

Inclusion Criteria:
1. Patients with a disorder of orthostatic tolerance
2. No known disorder of orthostatic tolerance (healthy controls)
4. Age between 18-85 years
5. Male and female participants are eligible
6. Able and willing to provide informed consent
Exclusion Criteria:
1. Unable to give informed consent
2. An inability to safely withdraw from medicine(s) that could make test interpretation difficult or impossible
3. Other factors which in the investigator’s opinion would prevent the participant from completing the protocol, including poor compliance during previous studies or an unpredictable schedule

Study Location

University of Calgary
University of Calgary
Calgary, Alberta
Canada

Contact Study Team

Study Sponsored By
University of Calgary
Participants Required
More Information
Study ID: REB24-0750