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Exercise in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension | Pulmonary Function | Exercise | Cardiovascular | Lung Transplant |...

The hallmark symptoms of pulmonary arterial hypertension are shortness of breath and exercise intolerance. Current clinical drug therapies target relaxing the blood vessels in the lungs (pulmonary arteries), as shortness of breath and exercise intolerance may be a result of impaired lung blood vessel function. We are conducting a study to better understand how the lung blood vessels may contribute to shortness of breath and exercise intolerance in pulmonary arterial hypertension.

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Participation Requirements

  • Sex:

    Female, Intersex, Any, Male

  • Eligible Ages:

    18 to 80

Participation Criteria

Inclusion Criteria:
1. Diagnosis of group 1 pulmonary hypertension
2. Diagnosis of scleroderma
3. Newly diagnosed PAH
4. Double lung transplant recipient
5. Disease free control
6. HFpEF.
7. CTEPH.
8. COPD
Exclusion Criteria:
1. Diagnosis of group 2-5 pulmonary hypertension (secondary pulmonary hypertension) or related conditions (pre-existing heart, lung, or other cardiovascular conditions).
2. Obesity (body mass index greater than 35 kg/m^2)
3. A physical condition that may interfere with riding a stationary bike (e.g. severe hip arthritis)

Study Location

University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contact Study Team

Primary Contact

Andrew Brotto

[email protected]
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Study Sponsored By
University of Alberta
Participants Required
More Information
Study ID: Pro00120572