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A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study

Propionic Acidemia

The main purpose of this study is to evaluate the long-term safety of mRNA-3927 administered to participants with propionic acidemia (PA) who have previously participated in Study mRNA-3927-P101 (NCT04159103).

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Conditions de participation

  • Sexe:

    ALL
  • Âges admissibles:

    1 and up

Critères de participation

Inclusion Criteria:

* Participated in Study mRNA-3927-P101.
* Completed the EOT Visit in Study mRNA-3927-P101 within 10 days of first dose of mRNA-3927 in current study.

Exclusion Criteria:

* Not expected to receive clinical benefit from continued mRNA-3927 administration, in the opinion of the Investigator.
* Any clinical or laboratory abnormality or medical condition that, at the discretion of the Investigator, may put the individual at increased risk by participating in this study.
* History of liver and/or kidney transplant.

Lieu de l'étude

Hospital For Sick Children
Hospital For Sick Children
Toronto, Ontario
Canada

Contactez l'équipe d'étude

Étude parrainée par
ModernaTX, Inc.
Participants recherchés
Plus d'informations
ID de l'étude: NCT05130437