A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study
Propionic AcidemiaThe main purpose of this study is to evaluate the long-term safety of mRNA-3927 administered to participants with propionic acidemia (PA) who have previously participated in Study mRNA-3927-P101 (NCT04159103).
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Participation Requirements
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Sex:
ALL -
Eligible Ages:
1 and up
Participation Criteria
Inclusion Criteria:
* Participated in Study mRNA-3927-P101.
* Completed the EOT Visit in Study mRNA-3927-P101 within 10 days of first dose of mRNA-3927 in current study.
Exclusion Criteria:
* Not expected to receive clinical benefit from continued mRNA-3927 administration, in the opinion of the Investigator.
* Any clinical or laboratory abnormality or medical condition that, at the discretion of the Investigator, may put the individual at increased risk by participating in this study.
* History of liver and/or kidney transplant.
Study Location
Hospital For Sick Children
Hospital For Sick ChildrenToronto, Ontario
Canada
Contact Study Team
- Study Sponsored By
- ModernaTX, Inc.
- Participants Required
- More Information
- Study ID:
NCT05130437