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Non-Invasive Mapping of Cerebral Autoregulation Using Near Infrared Spectroscopy

Cerebral Autoregulation Mapping

The investigators propose to employ advanced multi-channel near non-invasive near infrared spectroscopy (NIRS) system married with entirely non-invasive continuous arterial blood pressure (niABP) monitor to create a new wearable and portable imaging system that derives CA maps of the entire brain with high sampling rates at each point.

The objectives of this project are as follows:

1. To perform in vivo testing and optimization of the device using a block-trial design to evaluate the CA mapping system's performance during various perturbations.
2. To explore the impact of aging and sex on regional disparities in CA in a healthy volunteer population using static recording along with perturbation testing.

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Participation Requirements

  • Sex:

    ALL
  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* Healthy volunteers (male and female)
* Age \> 17

Exclusion Criteria:

* History of neurological illness
* History of systemic vascular
* History of cerebrovascular disease

Study Location

Health Sciences Centre (HSC)
Health Sciences Centre (HSC)
Winnipeg, Manitoba
Canada

Contact Study Team

Primary Contact

Frederick A Zeiler, MD PhD FRCSC

[email protected]
(204) 775-0055
Study Sponsored By
University of Manitoba
Participants Required
More Information
Study ID: NCT05433129