Robotic Evaluations of Motor Learning During Stroke Neurorehabilitation

Participation Requirements

• Sex:

  ALL

• Eligible Ages:

  18 and up

Participation Criteria

Inclusion Criteria for Stroke Participants:

* First time, unilateral ischemic stroke in middle cerebral artery territory, motor and/or sensory tracts and confirmed by clinical examination (including neuroimaging)
* 7±6 days post-stroke
* Upper limb impairment
* \>18 years old
* Fugl-Meyer upper extremity score between 30 and 57
* Vision better than 20/50 (corrected)
* Able to follow 3-step task commands

Inclusion Criteria for Control Participants:

* \>18 years old
* Good health

Exclusion Criteria for Stroke Participants:

* History of:

1. past undiagnosed stroke (evident on neuroimaging),
2. neglect (screened with Behavioral Inattention Test),
3. apraxia, or
4. upper extremity orthopedic or muscular issues
* Secondary neurologic injury or disease (e.g., Parkinson's)
* Contraindication to MRI
* Medical or neuropsychiatric conditions that would interfere with study outcomes, or where participation presents a risk to the subject
* Enrollment in an interventional trial that supplements standard therapy

Exclusion Criteria for Control Participants:

• Significant upper limb neurologic or orthopedic conditions