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Patent Foramen Ovale (PFO) and Risk of Perioperative Stroke

Patent Foramen Ovale

This is a multi-centre, prospective cohort study to determine if asymptomatic PFO is a risk factor for developing perioperative overt and covert stroke in patients undergoing non-cardiac surgery.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

1. patients 18 years and above;
2. referred for an elective, non-cardiac, non-vascular and non-brain surgery;
3. with an estimated hospital length of stay ≥2 days. We will include patients referred for general, orthopedic, urological, gynecologic, spinal or thoracic surgery.

Exclusion Criteria:

1. patients in need for long-term, perioperative anticoagulants;
2. those with comorbidities that potentially increase the risk of perioperative stroke;
3. contraindications to MRI;
4. unable to complete or adhere to the study.

Study Location

Toronto General Hospital, UHN
Toronto General Hospital, UHN
Toronto, Ontario
Canada

Contact Study Team

Primary Contact

Lusine Abrahamyan, MD

[email protected]
416-340-4800
Study Sponsored By
University Health Network, Toronto
Participants Required
More Information
Study ID: NCT05592301