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Improving Health Outcomes With Kefir

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Systemic Inflammatory Response

The purpose of the study is to ascertain whether traditional kefir not only enhances vascular health but also contributes to improved immune outcomes in both male and female participants at higher risk or living with Type 2 Diabetes (T2D) after 12 weeks of treatment.

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Conditions de participation

  • Sexe:

    ALL
  • Âges admissibles:

    24 to 70

Critères de participation

Inclusion Criteria:

1. females and males (24-70 years old) living in Edmonton (or Edmonton area/driving distance);
2. overweight or obesity (BMI \>25 Caucasian, \>23 Asian);
3. at higher risk of T2D (fasting blood glucose ≥ 5.6 - 6.9 mmol/L or/and HbA1C ≥ 5.5 - 6.4%); or
4. with diagnosis of T2D (fasting blood glucose ≥ 7.0 mmol/L or/and HbA1C ≥ 6.5%).

Exclusion Criteria:

1. a usual high intake (maximum intake 3 servings/week) of fermented foods excluding cheese (i.e., kefir, kombucha, kimchi, etc.) for the past 3 months;
2. gastrointestinal (GI) disorders of any kind;
3. being pregnant or breastfeeding;
4. monogenic dyslipidemias and endocrine disorders except for diabetes;
5. use of medications within the last 3 months (i.e., antibiotics or antifungals, corticosteroids, methotrexate, or immunosuppressive cytotoxic agents);
6. any health conditions deemed to interfere with primary outcomes at the investigator's discretion (e.g., kidney disease, liver disease, cancer, GI surgery, heavy alcohol consumption, etc.);
7. having a pacemaker or any electrical medical device that prevents the individual from undergoing the bioelectrical impedance analysis bioimmunoassay (BIA) test."

Lieu de l'étude

Human Nutrition Research Unit (HNRU)
Human Nutrition Research Unit (HNRU)
Edmonton, Alberta
Canada

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University of Alberta
University of Alberta
Edmonton, Alberta
Canada

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Primary Contact

Paulina Aldana Hernandez, PhD

[email protected]
780-492-9506
Étude parrainée par
University of Alberta
Participants recherchés
Plus d'informations
ID de l'étude: NCT06695221