Deep Repetitive Transcranial Magnetic Stimulation for Cannabis Use Disorder

Conditions de participation

• Sexe:

  ALL

• Âges admissibles:

  25 to 65

Critères de participation

Inclusion Criteria:

* Adult, age 25-65
* DSM-5 CUD, moderate or higher (4+ DSM-5 symptoms)
* 4 or more days of cannabis use per week
* Reports inhalation as one route of administration
* Treatment-seeking (i.e., self-reported readiness to change of 5 or greater on a 0-10 readiness ruler)
* Stable domicile and reliable transportation, and willingness to attend in-person visits at SJHH Hamilton.

Exclusion Criteria:

* Current psychotic symptoms, history of schizophrenia-spectrum disorders or bipolar disorder, or current PTSD
* Active suicidality (past 3 months) or history of severe suicidality (i.e., requiring hospitalization)
* Any other mental health condition deemed incompatible by the team
* High risk alcohol involvement and/or 4+ symptoms of alcohol use disorder
* Unstable management of an existing mental health condition or anticipation of a change to the treatment over the next 3 months
* Current unstable medical condition (e.g., diabetes)
* rTMS Contraindications: intracranial or metal implants in the head or nearby regions that cannot be safely removed; history of epilepsy or seizures; pregnancy (female participants only); pacemaker and/or implantable cardioverter-defibrillators).
* Medication contraindications (e.g., bupropion \>300 mg/day due to risk of seizures, benzodiazepine equivalent dose to lorazepam \>2 mg/day).
* History of recurrent headache or migraine (past year)
* Significant literacy, visual, or hearing problems
* Co-enrollment in a clinical drug trial