Nitrate Mouth Rinse and the Oral Microbiome
Nitric Oxide | Oral MicrobiomeThe study is aimed to determine if changes to the oral microbiome occur after the use of a nitrate rich mouth rinse. Participants with be asked to use either a controlled (water) mouthrinse once daily for 2 weeks while maintaining normal oral hygiene practices, or use the nitrate rich mouthrinse once daily for 2 weeks.
Primary Outcome measures:
-changes in the composition of the oral microbiome
Secondary Outcome measures
* Blood Pressure
* Salivary Nitric Oxide Levels
null
Participation Requirements
-
Sex:
ALL -
Eligible Ages:
18 to 40
Participation Criteria
Inclusion Criteria:
* You are between the ages of 18 and 40. Have no uncontrolled systemic diseases.
Participants with mild chronic conditions such as:
* Asthma
* Type 1 Diabetes Mellitus
Exclusion Criteria:
* You are under the age of 18.
* You have uncontrolled systemic diseases, or acute infections.
* You are taking prescription, antibiotics, probiotics, or antimicrobial mouthrinses.
* You have a documented true allergy (i.e Hives, Swelling of lips/throat) Soy, Nuts, Seeds, Dairy, Egg products, Fish/Shellfish or Wheat.
* The presence of acute or chronic oral conditions including:
* Herpes Simplex Virus (recent cold sores)
* Stomatitis
* Oral Lichen Planus
* Angular Cheilitis
* Candidiasis
* Necrotizing Gingival Diseases
* Other inflammatory or infectious pathologies
* Active dental caries "cavities"
* Any other periodontal diagnosis other than 'Healthy Periodontium' or localized gingivitis
Study Location
Dalhousie University
Dalhousie UniversityHalifax, Nova Scotia
Canada
Contact Study Team
- Study Sponsored By
- Dalhousie University
- Participants Required
- More Information
- Study ID:
NCT06588049