Healthy Lung Study- Development of 3T MRI Hardware and Software for 3He Gas Imaging of the Lung: Healthy Volunteer Development Study
Healthy VolunteersHealthy volunteers aged 18-75 will undergo hyperpolarized 3-Helium MRI and pulmonary function testing for the development of tools to assess image signal to noise and reproducibility of spin-density and diffusion-weighted imaging.
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Participation Requirements
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Sex:
ALL -
Eligible Ages:
18 to 75
Participation Criteria
Inclusion Criteria:
* Able to perform a breath hold for up to 16 seconds.
* BMI between 18 and 40.
* Stable health on the basis of medical history.
* Smoking history \< 1 pack/year.
Exclusion Criteria:
* Patient is, in the opinion of the investigator, mentally or legally incapacitated, preventing informed consent from being obtained, or cannot read or understand the written material.
* Subject has a daytime room air oxygen saturation \<90% while lying supine.
* Patient is unable to perform spirometry or plethysmography maneuvers
* Patient is pregnant
* In the investigator's opinion, subject suffers from any physical, psychological or other condition(s) that might prevent performance of the MRI, such as severe claustrophobia.
* Subject has an implanted mechanically, electrically or magnetically activated device or any metal in their body which cannot be removed, including but not limited to pacemakers, neurostimulators, biostimulators, implanted insulin pumps, aneurysm clips, bioprosthesis, artificial limb, metallic fragment or foreign body, shunt, surgical staples (including clips or metallic sutures and/or ear implants.)
Study Location
Robarts Research Institute; The University of Western Ontario; London Health Sciences Centre
Robarts Research Institute; The University of Western Ontario; London Health Sciences CentreLondon, Ontario
Canada
Contact Study Team
- Study Sponsored By
- Western University, Canada
- Participants Required
- More Information
- Study ID:
NCT03169673