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Cognitive and Physical Training in Patients With Chronic Obstructive Pulmonary Disease Patients

Pulmonary Disease, Chronic Obstructive

Cognitive and physical function impairments are common in patients diagnosed with Chronic Obstructive Pulmonary Disease (COPD). Research has shown that cognitive and physical exercise training may be a beneficial strategy to improve physical and cognitive performance in COPD patients; however, interventions combining physical and cognitive training have not been evaluated in this population. The objectives of this research are i) to evaluate the feasibility of an 8-week home-based cognitive-physical training program in COPD patients; and ii) to derive preliminary estimates on intervention efficacy with cognitive-physical training on dual-task performance, physical function, activities of daily living, and health-related quality of life. Related to our research objectives, we hypothesize that i) it will be feasible to safely recruit COPD patients into a home-based cognitive physical training program with 75% adherence and high satisfaction ratings with the prescribed training; and that ii) the combination of cognitive and physical training will be superior to physical training alone for improving dual-task and cognitive performance, physical function, activities of daily living, and health-related quality of life.

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Conditions de participation

  • Sexe:

    ALL
  • Âges admissibles:

    50 and up

Critères de participation

Inclusion Criteria:

* Adult participants (≥ 50 years of age)
* Clinical and spirometric diagnosis of COPD (FEV1 30-80%)
* Access to reliable internet connection
* Ability to mobilize independently and safely, with or without a walking aid

Exclusion Criteria:

* Current participation in a pulmonary rehabilitation program
* Disease exacerbation in the past 3 months
* Diagnosis of a neurological or musculoskeletal condition that would interfere with safe performance of study tests (e.g., stroke, myopathy, inflammatory arthritis)
* Severe cognitive impairment ascertained by chart review or self-reported
* Coronary artery disease, pacemaker or implantable defibrillator, clinical diagnosis of congestive heart failure (CHF), or poorly controlled arrhythmias
* Medical instability (hepatic dysfunction, metabolic abnormalities, or active infection)
* Overt psychiatric disorder or substance abuse
* Patient on home oxygen therapy
* Insufficient English fluency and cognition to carry out testing and training
* Patient actively listed for lung transplantation

Lieu de l'étude

University Health Network
University Health Network
Toronto, Ontario
Canada

Contactez l'équipe d'étude

Primary Contact

Dmitry Rozenberg, MD, PhD

[email protected]
416-340-4800
Étude parrainée par
University Health Network, Toronto
Participants recherchés
Plus d'informations
ID de l'étude: NCT05140226